Chapter 24 The Burden

Cancer in Latin America and the Caribbean

The rising cancer burden in the region reflects the rapid adoption of more westernized lifestyles at the population level.

The Latin America and the Caribbean (LAC) region has doubled in population size over the last half-century to 665 million inhabitants today. About 1.5 million new cancer cases and 741,000 cancer deaths, excluding non-melanoma skin cancers, are estimated to occur in the LAC region in 2022. The five most common cancers are prostate (226,000 new cases per year, 15%), female breast (220,000, 15%), colorectal (145,000, 10%), lung (105,000, 7%) and stomach (74,000, 5%) (Figure 24.1). Lung cancer is the leading cause of cancer death (91,000, 12%) followed by colorectal (74,000 10%), prostate (61,000, 8%), female breast (60,000, 8%) and stomach (58,000, 8%) cancers.

Figure 24.1

Estimated number of new cancer cases and deaths by type (excluding non-melanoma skin cancer) in Latin America and the Caribbean, 2022

Prostate
Breast
Colorectum
Lung
Stomach
Thyroid
Liver
Other specified cancers

Cancer rates vary markedly in the region, with all-cancer incidence in both sexes ranging from 263 (per 100,000) in Uruguay to 106 (per 100,000) in Belize, and mortality from 128 to 60 in the same countries, respectively (Map 24.1).

Breast cancer is the leading cause of cancer death among women in almost all LAC countries, though cervical cancer leads in Belize, Honduras, and El Salvador in Central America and in Bolivia and Peru in South America. In males, prostate cancer is the leading cause of cancer death in 25 countries in the region, notably in Central America and the Caribbean, while lung cancer is the most frequent cause of cancer death in Argentina, Bolivia, Brazil, Cuba, and Uruguay (Map 24.2).

Lung cancer rates considerably vary across countries partly due to differences in the implementation of tobacco-control measures. Tax hikes in Brazil and Uruguay beginning in 2005 and 2006, respectively, have led to a reduction in smoking prevalence in recent years.

Uruguay became the first country in the region to implement plain tobacco packaging in 2018.

Nevertheless, the increasing cancer burden in the LAC countries reflects a multitude of sociodemographic changes across the region in the last decades.

Sources

Text

  • Bray F, Laversanne M, Weiderpass E, Soerjomataram I. The ever-increasing importance of cancer as a leading cause of premature death worldwide. Cancer. Aug 15 2021;127(16):3029-3030. doi:10.1002/cncr.33587
  • Piñeros M, Laversanne M, Barrios E, et al. An updated profile of the cancer burden, patterns and trends in Latin America and the Caribbean. Lancet Reg Health Am. Sep 2022;13:None. doi:10.1016/j.lana.2022.100294
  • Bray F, Colombet M, Aitken JF, Bardot A, Eser S, Galceran J, Hagenimana M, Matsuda T, Mery L, Piñeros M, Soerjomataram I, de Vries E, Wiggins C, Won Y-J, Znaor A, Ferlay J, editors (2023). Cancer Incidence in Five Continents, Vol. XII (IARC Cancer Base No. 19). Lyon: International Agency for Research on Cancer. https://ci5.iarc.who.int.
  • Barrios CH, Werutsky G, Mohar A, et al. Cancer control in Latin America and the Caribbean: recent advances and opportunities to move forward. Lancet Oncol. Nov 2021;22(11):e474-e487. doi:10.1016/s1470-2045(21)00492-7
  • Carvalho de Souza M, Giunta DH, Szklo AS, Almeida LM, Szklo M. The tobacco epidemic curve in Brazil: Where are we going? Cancer Epidemiol. Aug 2020;67:101736. doi:10.1016/j.canep.2020.101736
  • Alonso R, Piñeros M, Laversanne M, et al. Lung cancer incidence trends in Uruguay 1990-2014: An age-period-cohort analysis. Cancer Epidemiol. Aug 2018;55:17-22. doi:10.1016/j.canep.2018.04.012
  • Comision Economica para Amercia Latina y El Caribe C. Los efectos y desafios de la transformacion demografica en America Latina y El Caribe: CEPAL; 2018. https://www.cepal.org/es/enfoques/efectos-desafios-la-transformacion-demografica-america-latina-caribe.

Maps

  • Maps 24.1-24.4: Ferlay J, Ervik M, Lam F, Laversanne M, Colombet M, Mery L, Piñeros M, Znaor A, Soerjomataram I, Bray F (2024). Global Cancer Observatory: Cancer Today (version 1.1). Lyon, France: International Agency for Research on Cancer. https://gco.iarc.who.int/today.

Figures

  • Figure 24.1: Ferlay J, Ervik M, Lam F, Laversanne M, Colombet M, Mery L, Piñeros M, Znaor A, Soerjomataram I, Bray F (2024). Global Cancer Observatory: Cancer Today (version 1.1). Lyon, France: International Agency for Research on Cancer. https://gco.iarc.who.int/today.